June 2012

Apparently Ice-T and Ice Cube are ready to do a collaboration the Feel Good Depot Way!!

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If your like me, sometimes you just see something and think to yourself….

You Freaking deserve whatever happens to you in this one.

Welcome to the First Edition of Friday Idiots…

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This is a Feel Good Depot Type Gadget.

http://www.sciencedaily.com/releases/2012/06/120627142512.htm

The microparticles consist of a single layer of lipids (fatty molecules) that surround a tiny pocket of oxygen gas, and are delivered in a liquid solution. In a cover article in the June 27 issue of Science Translational Medicine, John Kheir, MD, of the Department of Cardiology at Boston Children’s Hospital, and colleagues report that an infusion of these microparticles into animals with low blood oxygen levels restored blood oxygen saturation to near-normal levels, within seconds.

When the trachea was completely blocked — a more dangerous “real world” scenario — the infusion kept the animals alive for 15 minutes without a single breath, and reduced the incidence of cardiac arrest and organ injury.

The microparticle solutions are portable and could stabilize patients in emergency situations, buying time for paramedics, emergency clinicians or intensive care clinicians to more safely place a breathing tube or perform other life-saving therapies, says Kheir.

“This is a short-term oxygen substitute — a way to safely inject oxygen gas to support patients during a critical few minutes,” he says. “Eventually, this could be stored in syringes on every code cart in a hospital, ambulance or transport helicopter to help stabilize patients who are having difficulty breathing.”

The microparticles would likely only be administered for a short time, between 15 and 30 minutes, because they are carried in fluid that would overload the blood if used for longer periods, Kheir says.

Kheir also notes that the particles are different from blood substitutes, which carry oxygen but are not useful when the lungs are unable to oxygenate them. Instead, the microparticles are designed for situations in which the lungs are completely incapacitated.

Kheir began investigating the idea of injectable oxygen in 2006, after caring for a little girl who sustained a severe brain injury resulting from a severe pneumonia that caused bleeding into her lungs and severely low oxygen levels. Despite the team’s best efforts, she died before they could place her on a heart-lung machine. Frustrated by this, Kheir formed a team to search for another way to deliver oxygen.

“Some of the most convincing experiments were the early ones,” he says. “We drew each other’s blood, mixed it in a test tube with the microparticles, and watched blue blood turn immediately red, right before our eyes.”

Over the years, Kheir and his team have tested various concentrations and sizes of the microparticles to optimize their effectiveness and to make them safe for injection. “The effort was truly multidisciplinary,” says Kheir. “It took chemical engineers, particle scientists and medical doctors to get the mix just right.”

In the studies reported in the paper, they used a device called a sonicator, which uses high-intensity sound waves to mix the oxygen and lipids together. The process traps oxygen gas inside particles averaging 2 to 4 micrometers in size (not visible without a microscope). The resulting solution, with oxygen gas making up 70 percent of the volume, mixed efficiently with human blood.

“One of the keys to the success of the project was the ability to administer a concentrated amount of oxygen gas in a small amount of liquid,” Kheir says. “The suspension carries three to four times the oxygen content of our own red blood cells.”

Intravenous administration of oxygen gas was tried in the early 1900s, but these attempts failed to oxygenate the blood and often caused dangerous gas embolisms.

“We have engineered around this problem by packaging the gas into small, deformable particles,” Kheir explains. “They dramatically increase the surface area for gas exchange and are able to squeeze through capillaries where free gas would get stuck.”

The study was funded by three awards from the Technology Development Fund at Boston Children’s Hospital Boston and a U.S. Department of Defense Basic Research Award to Kheir

 

Hopefully these make it to emergency workers and FAST.

YOU PEOPLE TOTALLY FREAKING ROCK!!!!


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Sometimes a scene can be so awesome that you can be at a loss of words for a bit!!!

This is one of those times.

On June 9, 2012 this guy told his fiancee Allison to meet me him in Bryant Park for lunch. When she arrived he had her close friend meet her and walk her toward the steps of the park. Then, a woman unknown to Allison, came up and led her to the center table for a little show.

 He also had family and friends waiting on the side with instructions to pop out and join the band when they heard the song “Hey Baby, I wanna know if you’ll be my girl”!

EPIC and he sincerely made it difficult for men all over the world to top that. You ROCK DUDE!!

She is one lucky lady and awesome because too because what sparked this it seems is that she embarrassed him by planning a costume party and having him dress as Fred Flintstones only for him to show up and find everyone in a tux!!!!

Congrats to you both and may you have a long, loving life together.

 

And on that note, here is another AWESOME wedding proposal that will probably have you in tears!!

Howie Mandel and the Show “Mobbed” hooked this young couple up and it is BEYOND AMAZING!!!!

This truly made my day…. WOW!!

Now that is doing it in the Feel Good Depot Kind of Way!!!

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Monday Morning Commute – The Feel Good Depot Way

June 24, 2012

Imagine, you’re driving to work and you look to your left…. WTF??? LOL – Simply Genius. This guy Rocks!!

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It’s Friday @ The Feel Good Depot

June 22, 2012

Friday, oh how I have missed you!!!

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Lebron James vs Kobe Bryant vs Michael Jordan – Who Is The Best Ever??

June 21, 2012

Sometimes you have to break things down visually so people can understand what you are trying to convey. Here at the Feel Good Depot, we are firm believers in that mindset. Who is the best??? Let me make it EASY for you… You all ROCK but in the end… there can be only one!!!!  

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Working From Home Issues – The Feel Good Depot Way

June 21, 2012

When you work from home… getting all dressed up becomes a chore. You know you have been working from home too long when your significant other asks you “why are you all dressed up” when you put on Jeans and a T-Shirt.

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Vacationer makes life-saving rescues two days in a row

June 19, 2012

Gus Hertz… REMEMBER that name. If you are ever in a situation where you need a miracle… He is apparently your MAN and somewhere I think he might be hiding a suit with a Cape!! The Virginia man helped save three lives in two separate crashes on back-to-back days while on vacation in St. Petersburg, Fla., this week. First, he and […]

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Red Solo Cup Measuring Device – The Feel Good Depot Way

June 17, 2012

Did you know the lines on a Red Solo Cup are actually there for a reason. If not, to help with Father’s Day measurements sure to happen today… here you are. It’s Feel Good Depot AWESOME type knowledge. As they say on TV. Stay Thirsty My Friends!!

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